TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
University of Leipzig
Curated by ChEMBL
University of Leipzig
Curated by ChEMBL
Affinity DataKi: 0.00200nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
University of Leipzig
Curated by ChEMBL
University of Leipzig
Curated by ChEMBL
Affinity DataKi: 0.00600nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
University of Leipzig
Curated by ChEMBL
University of Leipzig
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
University of Leipzig
Curated by ChEMBL
University of Leipzig
Curated by ChEMBL
Affinity DataKi: 0.0200nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
University of Leipzig
Curated by ChEMBL
University of Leipzig
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nM Kon: 0.000127M-1s-1 Koff: 9.36E+4s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 1.43nM Kon: 0.000142M-1s-1 Koff: 9.93E+4s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
University of Leipzig
Curated by ChEMBL
University of Leipzig
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
University of Leipzig
Curated by ChEMBL
University of Leipzig
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Displacement of [125I-Tyr10] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.73nM Kon: 0.00358M-1s-1 Koff: 1.31E+6s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 4.02nM Kon: 0.0000628M-1s-1 Koff: 1.56E+4s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Tested for its binding affinity at adenosine A1 receptor in rat brain cortical membrane preparations using [3H]-CCPA as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 5.61nM Kon: 0.000429M-1s-1 Koff: 7.64E+4s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 5.70nMAssay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 5.74nM Kon: 0.00156M-1s-1 Koff: 2.72E+5s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 5.80nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 6.70nMAssay Description:Tested for its binding affinity at adenosine A1 receptor in rat brain cortical membrane preparations using [3H]-CCPA as a radioligandMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
University of Leipzig
Curated by ChEMBL
University of Leipzig
Curated by ChEMBL
Affinity DataKi: 8.40nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 8.80nMAssay Description:Binding affinity against adenosine A1 receptor expressed in CHO cells using [3H]-CCPAMore data for this Ligand-Target Pair
Affinity DataKi: 10.7nM Kon: 0.000130M-1s-1 Koff: 1.22E+4s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
University of Leipzig
Curated by ChEMBL
University of Leipzig
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
University of Leipzig
Curated by ChEMBL
University of Leipzig
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Displacement of [125I-Tyr10] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Tested for its binding affinity at adenosine A1 receptor in rat brain cortical membrane preparations using [3H]-CCPA as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 16.3nM Kon: 0.0000612M-1s-1 Koff: 3.75E+3s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 17.9nM Kon: 0.0000292M-1s-1 Koff: 1.63E+3s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Tested for its binding affinity at adenosine A1 receptor in rat brain cortical membrane preparations using [3H]-CCPA as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Inhibition of human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 35nM Kon: 0.000567M-1s-1 Koff: 1.62E+4s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 42nM Kon: 0.000134M-1s-1 Koff: 3.20E+3s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 44nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Tested for its binding affinity at adenosine A1 receptor in rat brain cortical membrane preparations using [3H]-CCPA as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 51nM Kon: 0.0000515M-1s-1 Koff: 1.01E+3s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 75.5nM Kon: 0.0000850M-1s-1 Koff: 1.13E+3s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
University of Leipzig
Curated by ChEMBL
University of Leipzig
Curated by ChEMBL
Affinity DataKi: 77nMAssay Description:Displacement of [125I-Tyr10] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 91nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 101nM Kon: 0.000354M-1s-1 Koff: 3.54E+3s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 133nM Kon: 0.0000292M-1s-1 Koff: 219s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 145nM Kon: 0.000201M-1s-1 Koff: 1.39E+3s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 238nM Kon: 0.000163M-1s-1 Koff: 6.85E+5s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Tested for its binding affinity at adenosine A1 receptor in rat brain cortical membrane preparations using [3H]-CCPA as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
Affinity DataKi: 290nM Kon: 0.0000692M-1s-1 Koff: 239s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
Affinity DataKi: 310nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Leipzig
University of Leipzig
Affinity DataKi: 340nM IC50: 750nMAssay Description:For competition-based fluorescence polarization assays, the ability of the test compounds to displace fluorophore-labeled peptides from their respect...More data for this Ligand-Target Pair
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Leipzig
University of Leipzig
Affinity DataKi: 390nM IC50: 860nMAssay Description:For competition-based fluorescence polarization assays, the ability of the test compounds to displace fluorophore-labeled peptides from their respect...More data for this Ligand-Target Pair