Compile Data Set for Download or QSAR
Found 321 from University of Leipzig
LigandPNGBDBM50180775(CHEMBL386763 | FV-Aib-TDVGPFAF | [Aib29,Asp31,Pro3...)copy SMILEScopy InChI
Affinity DataKi:  0.00200nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280526HPubMed
LigandPNGBDBM50180778(CHEMBL2371891 | FV-Hyp-TDVGPFAF)copy SMILEScopy InChI
Affinity DataKi:  0.00600nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280526HPubMed
LigandPNGBDBM50180781(CHEMBL2371890 | FV-Tic-TDVGPFAF)copy SMILEScopy InChI
Affinity DataKi:  0.0200nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280526HPubMed
LigandPNGBDBM50062162(CHEMBL264010 | FVPTDVGPFAF)copy SMILEScopy InChI
Affinity DataKi:  0.0200nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280526HPubMed
LigandPNGBDBM50180777(CHEMBL427759 | FV((1R,2R,3R)-beta-aminocyclopropan...)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280526HPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50064310(2-Ethoxy-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d...)copy SMILEScopy InChI
Affinity DataKi:  1.40nM Kon:  0.000127M-1s-1 Koff:  9.36E+4s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KNFPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50064318(2-Propoxy-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-...)copy SMILEScopy InChI
Affinity DataKi:  1.43nM Kon:  0.000142M-1s-1 Koff:  9.93E+4s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KNFPubMed
LigandPNGBDBM50180776(CHEMBL2371892 | FVPTDVG-Tic-FAF-Tic)copy SMILEScopy InChI
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280526HPubMed
LigandPNGBDBM50180776(CHEMBL2371892 | FVPTDVG-Tic-FAF-Tic)copy SMILEScopy InChI
Affinity DataKi:  1.80nMAssay Description:Displacement of [125I-Tyr10] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280526HPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50064316(2-Ethylsulfanyl-5,6-dimethyl-thieno[2,3-d][1,3]oxa...)copy SMILEScopy InChI
Affinity DataKi:  2.73nM Kon:  0.00358M-1s-1 Koff:  1.31E+6s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KNFPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50064314(5,6-Dimethyl-2-propoxy-thieno[2,3-d][1,3]oxazin-4-...)copy SMILEScopy InChI
Affinity DataKi:  4.02nM Kon:  0.0000628M-1s-1 Koff:  1.56E+4s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KNFPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50014295(5,6-Dimethyl-2-phenyl-7-((R)-1-phenyl-ethyl)-7H-py...)copy SMILEScopy InChI
Affinity DataKi:  4.70nMAssay Description:Tested for its binding affinity at adenosine A1 receptor in rat brain cortical membrane preparations using [3H]-CCPA as a radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB450SPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50064325(2-Ethoxy-5-isopropyl-thieno[2,3-d][1,3]oxazin-4-on...)copy SMILEScopy InChI
Affinity DataKi:  5.61nM Kon:  0.000429M-1s-1 Koff:  7.64E+4s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KNFPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50064320(2-Ethylsulfanyl-5,6,7,8-tetrahydro-benzo[4,5]thien...)copy SMILEScopy InChI
Affinity DataKi:  5.70nMAssay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KNFPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50064326(2-Methylsulfanyl-5,6,7,8-tetrahydro-benzo[4,5]thie...)copy SMILEScopy InChI
Affinity DataKi:  5.74nM Kon:  0.00156M-1s-1 Koff:  2.72E+5s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KNFPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084235(2-Diethylamino-benzo[4,5]thieno[2,3-d][1,3]oxazin-...)copy SMILEScopy InChI
Affinity DataKi:  5.80nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936RGPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50051653((5,6-Dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrimidin-...)copy SMILEScopy InChI
Affinity DataKi:  6.70nMAssay Description:Tested for its binding affinity at adenosine A1 receptor in rat brain cortical membrane preparations using [3H]-CCPA as a radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB450SPubMed
LigandPNGBDBM50180783(CHEMBL385986 | FVATDVGPFAF)copy SMILEScopy InChI
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280526HPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50094591(5,6-Dimethyl-7-(1-phenyl-ethyl)-2-pyridin-4-yl-7H-...)copy SMILEScopy InChI
Affinity DataKi:  8.80nMAssay Description:Binding affinity against adenosine A1 receptor expressed in CHO cells using [3H]-CCPAMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB450SPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50064313(2-Ethoxy-5,6-dimethyl-thieno[2,3-d][1,3]oxazin-4-o...)copy SMILEScopy InChI
Affinity DataKi:  10.7nM Kon:  0.000130M-1s-1 Koff:  1.22E+4s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KNFPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084232(2-(diethylamino)-5-isopropyl-4H-thieno[2,3-d][1,3]...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936RGPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50064308(2-Diethylamino-5,6,7,8-tetrahydro-benzo[4,5]thieno...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936RGPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084233(2-Diethylamino-6,7-dihydro-5H-cyclopenta[4,5]thien...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936RGPubMed
LigandPNGBDBM50062214(CHEMBL406459 | FVPTDVGAFAF)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Displacement of [3H-propionyl-K24] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280526HPubMed
LigandPNGBDBM50062162(CHEMBL264010 | FVPTDVGPFAF)copy SMILEScopy InChI
Affinity DataKi:  14nMAssay Description:Displacement of [125I-Tyr10] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280526HPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50094599(2-Furan-2-yl-5,6-dimethyl-7-(1-phenyl-ethyl)-7H-py...)copy SMILEScopy InChI
Affinity DataKi:  16nMAssay Description:Tested for its binding affinity at adenosine A1 receptor in rat brain cortical membrane preparations using [3H]-CCPA as a radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB450SPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50064308(2-Diethylamino-5,6,7,8-tetrahydro-benzo[4,5]thieno...)copy SMILEScopy InChI
Affinity DataKi:  16.3nM Kon:  0.0000612M-1s-1 Koff:  3.75E+3s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KNFPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50064322((4-Oxo-5,6,7,8-tetrahydro-4H-benzo[4,5]thieno[2,3-...)copy SMILEScopy InChI
Affinity DataKi:  17.9nM Kon:  0.0000292M-1s-1 Koff:  1.63E+3s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KNFPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50094589(5,6-Dimethyl-7-(1-phenyl-ethyl)-2-thiophen-2-yl-7H...)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Tested for its binding affinity at adenosine A1 receptor in rat brain cortical membrane preparations using [3H]-CCPA as a radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB450SPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50244756(2-(2,3,5,6-Tetrafluoropyridin-4-yl)-1,2-benzisothi...)copy SMILEScopy InChI
Affinity DataKi:  28nMAssay Description:Inhibition of human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M36NTPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50064319(5,6-Dimethyl-2-methylsulfanyl-thieno[2,3-d][1,3]ox...)copy SMILEScopy InChI
Affinity DataKi:  35nM Kon:  0.000567M-1s-1 Koff:  1.62E+4s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KNFPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50064315(2-Isopropylamino-thieno[2,3-d][1,3]oxazin-4-one | ...)copy SMILEScopy InChI
Affinity DataKi:  42nM Kon:  0.000134M-1s-1 Koff:  3.20E+3s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KNFPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084234(2-Diethylamino-6,7,8,9-tetrahydro-5H-3-oxa-10-thia...)copy SMILEScopy InChI
Affinity DataKi:  44nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936RGPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50094591(5,6-Dimethyl-7-(1-phenyl-ethyl)-2-pyridin-4-yl-7H-...)copy SMILEScopy InChI
Affinity DataKi:  46nMAssay Description:Tested for its binding affinity at adenosine A1 receptor in rat brain cortical membrane preparations using [3H]-CCPA as a radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB450SPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50064317(2-Isobutoxy-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,...)copy SMILEScopy InChI
Affinity DataKi:  51nM Kon:  0.0000515M-1s-1 Koff:  1.01E+3s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KNFPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50064324(2-Isopropylamino-5,6-dimethyl-thieno[2,3-d][1,3]ox...)copy SMILEScopy InChI
Affinity DataKi:  75.5nM Kon:  0.0000850M-1s-1 Koff:  1.13E+3s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KNFPubMed
LigandPNGBDBM50062214(CHEMBL406459 | FVPTDVGAFAF)copy SMILEScopy InChI
Affinity DataKi:  77nMAssay Description:Displacement of [125I-Tyr10] from halphaCGRP expressed in human neuroblastoma SK-N-MC cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280526HPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084227(2-(diethylamino)-5-methyl-4-oxo-4H-thieno[2,3-d][1...)copy SMILEScopy InChI
Affinity DataKi:  91nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936RGPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50064311(2-Benzylsulfanyl-5,6-dimethyl-thieno[2,3-d][1,3]ox...)copy SMILEScopy InChI
Affinity DataKi:  101nM Kon:  0.000354M-1s-1 Koff:  3.54E+3s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KNFPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084230(2-Diethylamino-thieno[3,2-d][1,3]oxazin-4-one | CH...)copy SMILEScopy InChI
Affinity DataKi:  130nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936RGPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50064309(2-Isobutoxy-5,6-dimethyl-thieno[2,3-d][1,3]oxazin-...)copy SMILEScopy InChI
Affinity DataKi:  133nM Kon:  0.0000292M-1s-1 Koff:  219s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KNFPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50064321(2-isopropylamino-5,6,7,8-tetrahydro-benzo[4,5]thie...)copy SMILEScopy InChI
Affinity DataKi:  145nM Kon:  0.000201M-1s-1 Koff:  1.39E+3s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KNFPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084229(2-Diethylamino-5-methyl-5,6,7,8-tetrahydro-benzo[4...)copy SMILEScopy InChI
Affinity DataKi:  210nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936RGPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50064312((5,6-Dimethyl-4-oxo-4H-thieno[2,3-d][1,3]oxazin-2-...)copy SMILEScopy InChI
Affinity DataKi:  238nM Kon:  0.000163M-1s-1 Koff:  6.85E+5s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KNFPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50094587(2-[4-Amino-5,6-dimethyl-7-(1-phenyl-ethyl)-7H-pyrr...)copy SMILEScopy InChI
Affinity DataKi:  240nMAssay Description:Tested for its binding affinity at adenosine A1 receptor in rat brain cortical membrane preparations using [3H]-CCPA as a radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SB450SPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084236(2-Diethylamino-thieno[2,3-d][1,3]oxazin-4-one | CH...)copy SMILEScopy InChI
Affinity DataKi:  260nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936RGPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50064323(2-Benzylsulfanyl-5,6,7,8-tetrahydro-benzo[4,5]thie...)copy SMILEScopy InChI
Affinity DataKi:  290nM Kon:  0.0000692M-1s-1 Koff:  239s-1Assay Description:Steady state inhibition constant for Human Leukocyte Elastase inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KNFPubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50084231(2-Diethylamino-benzo[d][1,3]oxazin-4-one | CHEMBL3...)copy SMILEScopy InChI
Affinity DataKi:  310nMAssay Description:Inhibitory activity of the compound was tested against human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K936RGPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Leipzig

LigandPNGBDBM165192(4-((8-Methylnonanamido)methyl)-1,2-phenylene bis(d...)copy SMILEScopy InChI
Affinity DataKi:  340nM IC50: 750nMAssay Description:For competition-based fluorescence polarization assays, the ability of the test compounds to displace fluorophore-labeled peptides from their respect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55M8GPubMed
TargetSignal transducer and activator of transcription 5B(Homo sapiens (Human))
University of Leipzig

LigandPNGBDBM165193(4-(Nonanamidomethyl)-1,2-phenylene bis(dihydrogen ...)copy SMILEScopy InChI
Affinity DataKi:  390nM IC50: 860nMAssay Description:For competition-based fluorescence polarization assays, the ability of the test compounds to displace fluorophore-labeled peptides from their respect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P55M8GPubMed
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